Product name: MAL-PEG-MAL

Product specification:1g、5g(Customized according to requirements）

PEG molecular weight：1K,2K, 5K, 10K, 20K, 40K

Product description

CAS NO. :--

Molecular formula：--

Appearance：Solid powder or viscous solid；white

Common solvents：Chloroform, methanol、DMSO。

Reminder：In order to obtain the best use effect of the product, the material should always be kept at a low temperature under dry conditions to avoid frequent thawing and freezing. 

In order to ensure the stability of the product, please note that the package can only be opened after constant temperature drying!.

Mal peg MAL is a bifunctional peg derivative. Maleimide peg is a sulfhydryl (mercaptan / SH) based reactive peg derivative, which can be used to selectively modify proteins, peptides or any other surface with available sulfhydryl groups. The reaction between maleimide and mercaptan is easy at pH 6.5 ~ 7.5 to form a stable sulfide bond.

The reaction between maleimide and mercaptan is easy at pH 6.5 ~ 7.5 to form a stable sulfide bond. Materials required: PEGylated buffer, PBS buffer, pH 7 or other pH 7 mercaptan free buffer. Maleimide stock solution: 100 mg in 1 ml coupling buffer, washing solution: distilled water or any aqueous buffer. Reaction step: dissolve the target substance in the binding buffer. Estimate the concentration of mercaptan group on the target substance, add maleimide peg stock solution to the target conjugate, and maintain the final concentration at least 10 mg / ml. The best combination requires 10 ~ 50 moles of excess peg maleimide, and the mixture is stirred at room temperature for 2 ~ 4 hours, or overnight at 4 ℃. The conjugate can be purified by size exclusion chromatography or dialysis. (for reference only)