Product name: PLGA,POLY(D,L-LACTIDE-CO-GLYCOLIDE)

Product specification:1g、5g(Customized according to requirements）

Product description：

CAS NO. 26780-50-7

Molecular formula：C10H12O8

Flash point：113℃

Storage conditions： 2-8°C

PLGA molecular weight: 1K, 2K, 5K, 10K, 15K, 20K, 30K, 40K, customizable

PLGA ratio: 50:50 / 75:25

Appearance：Solid powder or crystalline translucent solid

Common solvents：ethyl acetate, chloroform, acetone and THF: soluble。

Reminder：

In order to obtain the best use effect of the product, the material should always be kept at a low temperature under dry conditions to avoid frequent thawing and freezing. 

To ensure the stability of the product, please note that the package can only be opened after constant temperature drying!

PLGA is hydroxyl terminated, oh-plga-ho, PLGA is random copolymerization, amorphous polymer Poly (lactic acid glycolic acid), PLGA is a non functional side group copolymer polymerized by lactic acid and glycolic acid. It is an important biomedical polymer material. It has the advantages of polylactic acid (PLA) and polyglycolic acid (PGA), and has good biocompatibility and degradability.

It is widely used in surgical sutures, anti adhesion membranes, tissue engineering scaffolds, biomedical fields, fracture internal fixation materials, tissue repair materials and drug controlled release systems. Compared with PLA, it is flexible and degradable according to the content of GA. PLGA has excellent biocompatibility, biodegradability, low immunogenicity, low toxicity and good mechanical strength, Approved by the U.S. Food and Drug Administration (it is approved to be used as drug controlled-release carrier. This kind of material hydrolyzes the ester bond in the body to produce lactic acid monomer, and then oxidizes to keto acid under the action of lactate dehydrogenase. As an energy metabolite, it participates in the three acid cycle in the body, and finally converts into water and carbon dioxide, which is discharged from the body through the lungs, kidneys and skin. From being initially used to prevent the oxidation of vitamins to being recognized as biocompatible and biodegradable for drug delivery Hydrolytic materials have been used for decades. At present, they have very good development prospects in bone defect repair, protein, antitumor, polypeptide, vaccine and other drug carriers. Nanoscale, microsphere and gel prepared by PLGA can play a role in protecting drugs, increasing drug solubility and improving the bioavailability of drugs. It can achieve sustained release and controlled release for a long time, and has broad prospects for development.